Biologically Active Small Molecules, 459168-41-3
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JNJ-7777120
Cayman ChemicalA potent and selective histamine H4 receptor antagonist, with a Ki value of approximately 4 nM against the human, mouse, and rat H4 receptors; inhibits mast cell chemotaxis induced by 10 μM histamine (IC50 = 40 nM), reduces neutrophil influx in mouse peritonitis models (10 mg/kg s.c.), and…
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