A purine analog with immunosuppressive effects; serves as a prodrug for 6-mercaptopurine, which alters purine processing and DNA synthesis, interfering with lymphocyte proliferation; used to benefit IBD, as well as additional diseases with immunological or autoimmunological components.

Azathioprine is a purine analog that acts as a prodrug of mercaptopurine. Azathioprine exhibits anticancer chemotherapeutic, immunosuppressive, and antiviral activities. Azathioprine inhibits amidophosphoribosyl transferase, inhibiting the production of adenine and guanine purines and preventing…