Biologically Active Small Molecules, 14698-29-4
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Oxolinic Acid
Cayman ChemicalA quinolone antibiotic that inhibits bacterial DNA gyrase, but not eukaryotic topoisomerases, reversibly binding gyrase subunit A in gyrase-DNA complexes, blocking supercoiling activity and inhibiting DNA synthesis at 0.5-5 µg/ml; also blocks neuronal uptake of dopamine in mammals…
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