Biologically Active Small Molecules, 120964-45-6
1 - 1 of 1
Sort
View
Show
-
3-Deazaneplanocin A (hydrochloride)
Cayman ChemicalAn analog of 3-deazaadenosine, an inhibitor of SAH hydrolase; depletes EZH2 levels and inhibits trimethylation of lysine 27 on histone H3 in primary human AML cells in a dose-dependent manner (0.2-1 μM); acts synergistically with the pan-HDAC inhibitor panobinostat in inducing apoptosis of AML…
Site Search by