A natural meroterpene that has retinol-like effects on gene expression and properties of the skin; has antioxidant and antibacterial actions; inhibits DNA polymerase and UDP-glucuronosyltransferase 2B7 (IC50 = 41 µM).

Bakuchiol is a prenylated phenolic terpene originally sourced from many plants, including Psoralea coryfolia. Bakuchiol exhibits estrogenic, antibacterial, anti-inflammatory, anti-diabetic, anti-hyperlipidemic, and anti-fibrotic activities. Bakuchiol activates estrogen receptors, displaying…