CD45 is the common leukocyte antigen and is expressed on all cells of hematopoietic origin except erythrocytes. CD45 exists as a number of different isoforms which result from alternative RNA splicing of exons 4, 5 and 6. The I3/2.3 monoclonal antibody recognizes a framework epitope present on all…

Specificity: Reacts with the heavy and light chains of mouse IgG and the light chains of mouse IgM and IgA Source: Pepsin digest of Rabbit Anti-Mouse IgG(H+L) (SB Cat. No. 6175) Cross Adsorption: Pooled human sera and immunoglobulins; may react with immunoglobulins from other species …

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

Specificity: Reacts with human ? light chains Source: Pepsin digest of Goat Anti-Human Kappa, Mouse ads (SB Cat. No. 2061) Cross Adsorption: Human ? light chains; mouse immunoglobulins and pooled sera; may react with ? light chains from other species Purification: Isotype: Goat…

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

Specificity: Reacts with the heavy chain of mouse IgG2a Source: Pooled antisera from goats hyperimmunized with mouse IgG2a Cross Adsorption: Mouse IgG1, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

CD90 (Thy-1), a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes, and neurons of all mouse strains. The…

Specificity: Reacts with the heavy chain of rat IgM Source: Pooled antisera from goats hyperimmunized with rat IgM Cross Adsorption: Rat IgG; may react with immunoglobulins from other species Purification: Affinity chromatography on pooled rat IgM covalently linked to agarose Isotype: …

Ly-6G/Ly-6C, formerly known as the myeloid differentiation antigen Gr-1, is a GPI-anchored protein. In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. It is also transiently expressed on monocytes in the bone marrow. In the…

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

The monoclonal antibody DX5 reacts with CD49b, also known as very late antigen-2 (VLA-2) and a2 integrin. The antibody stains the majority of NK cells and a small subpopulation of T cells in all mouse strains tested (e.g., A/J, AKR, BALB/c, C3H/HeJ, C57BL/6, C57BL/10, C57BR, C58, CBA/Ca, CBA/J,…

Specificity: Reacts with the heavy and light chains of rabbit IgG and the light chains of rabbit IgM Source: Pooled antisera from goats hyperimmunized with rabbit IgG Cross Adsorption: Mouse, rat, and human immunoglobulins and pooled sera; may react with immunoglobulins from other species …

Specificity: Reacts with the heavy and light chains of human IgG, IgM, and IgA Source: Pepsin digest of Goat Anti-Human Ig (SB Cat. No. 2010) Cross Adsorption: None; may react with immunoglobulins from other species Purification: Isotype: Goat F(ab')2 IgG Format/Conjugate: UNLB…

Specificity: Reacts with the heavy and light chains of mouse IgG and the light chains of mouse IgM and IgA Source: Pooled antisera from donkeys hyperimmunized with mouse IgG Cross Adsorption: Human serum proteins (SP); may react with immunoglobulins from other species Purification: …

CD18 represents the common ß2 integrin subunit that associates non-covalently with the a/ß chains of CD11a, CD11b, and CD11c to form various integrin heterodimers. It is expressed strongly on lymphocytes and monocytes and weakly on granulocytes. CD18 mediates a variety of heterotypic and homotypic…

The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid…

Specificity: Reacts with the heavy chain of C57BL/6 mouse IgG2c Source: Pooled antisera from goats hyperimmunized with mouse IgG2c Cross Adsorption: Mouse IgG1, IgG2a, IgG2b, IgG3, IgM, and IgA; may react with immunoglobulins from other species Purification: Affinity chromatography on…

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

CD45RB represents an exon B-dependent form of CD45 glycoprotein. It is expressed at high density on peripheral B cells, the suppressor/cytotoxic subpopulation of T lymphocytes, a subset of helper T cells, most thymocytes, and at low density on macrophages and dendritic cells.

Specificity: Reacts with the heavy chain of mouse IgG1 Source: Pooled antisera from goats hyperimmunized with mouse IgG1 Cross Adsorption: Mouse IgG2a, IgG2b, IgG3, IgM, and IgA; human, bovine, and horse serum proteins (SP); may react with immunoglobulins from other species Purification: …

Specificity: Reacts with the heavy chain of mouse IgG2b Source: Pooled antisera from goats hyperimmunized with mouse IgG2b Cross Adsorption: Mouse IgG1, IgG2a, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

Specificity: Reacts with the heavy and light chains of turkey IgY Source: Pooled antisera from goats hyperimmunized with IgY Cross Adsorption: None; may react with immunoglobulins from other species and the light chains of other turkey immunoglobulins Purification: Affinity…

Specificity: Reacts with the heavy and light chains of rabbit IgG and the light chains of rabbit IgM Source: Pooled antisera from goats hyperimmunized with rabbit IgG Cross Adsorption: Mouse and human immunoglobulins and pooled sera; may react with immunoglobulins from other species …

CD22, also known as Lyb-8, is a heterodimeric transmembrane glycoprotein and a member of a structurally related group of immunoglobulin (Ig) superfamily domain-containing proteins called the sialoadhesin family. It is detected in the cytoplasm early in B cell development (late pro-B cell stage),…

The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid…

Specificity: Reacts with the heavy chain of mouse IgG1 Source: Pooled antisera from goats hyperimmunized with mouse IgG1 Cross Adsorption: Mouse IgG2a, IgG2b, IgG3, IgM, and IgA; may react with immunoglobulins from other species Purification: Affinity chromatography on mouse IgG1…

CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19…

Specificity: Reacts with the heavy chain of mouse IgG2a Source: Pooled antisera from goats hyperimmunized with mouse IgG2a Cross Adsorption: Mouse IgG1, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral…

Specificity: Reacts with the heavy and light chains of chicken IgY Source: Pooled antisera from goats hyperimmunized with IgY Cross Adsorption: None; may react with immunoglobulins from other species and the light chains of other chicken immunoglobulins Purification: Affinity…

Specificity: Reacts with the heavy and light chains of goat IgG Source: Pooled antisera from donkeys hyperimmunized with goat IgG Cross Adsorption: Human, mouse, rat, hamster, rabbit, chicken, horse, and guinea pig serum proteins (SP); may react with immunoglobulins from other species and…

Specificity: Reacts with the heavy chain of mouse IgG1 Source: Pepsin digest of Goat Anti-Mouse IgG1, Human ads (SB Cat. No. 1070) Cross Adsorption: Mouse IgG2a, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species …