CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is…

Specificity: Reacts with mouse ? light chains Source: Pooled antisera from goats hyperimmunized with mouse ? light chains Cross Adsorption: Mouse ? light chains; may react with ? light chains from other species Purification: Affinity chromatography on mouse ? light chains covalently…

Specificity: Reacts with the heavy and light chains of human IgG and the light chains of human IgM and IgA Source: Pooled antisera from rabbits hyperimmunized with human IgG Cross Adsorption: None; may react with immunoglobulins from other species Purification: Affinity chromatography on…

CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of ?d+ T cells to more mature T cells…

Specificity: Reacts with the heavy chain of mouse IgG3 Source: Pooled antisera from goats hyperimmunized with mouse IgG3 Cross Adsorption: Mouse IgG1, IgG2a, IgG2b, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …

CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86…

Specificity: Reacts with the heavy chain of mouse IgG1 Source: Pooled antisera from goats hyperimmunized with mouse IgG1 Cross Adsorption: Mouse IgG2a, IgG2b, IgG3, IgM, and IgA; human, bovine, and horse serum proteins (SP); may react with immunoglobulins from other species Purification: …

Specificity: Reacts with the heavy and light chains of rat IgG and the light chains of rat IgM Source: Pepsin digest of Rabbit Anti-Rat IgG(H+L) (SB Cat. No. 6180) Cross Adsorption: None; may react with immunoglobulins from other species and the light chains of other rat immunoglobulins …

Specificity: Reacts with the heavy and light chains of goat IgG Source: Pooled antisera from donkeys hyperimmunized with goat IgG Cross Adsorption: Human, mouse, rat, hamster, rabbit, chicken, horse, and guinea pig serum proteins (SP); may react with immunoglobulins from other species and…

CD90 (Thy-1), a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes, and neurons of all mouse strains. The…

Specificity: Reacts with the heavy and light chains of mouse IgG and the light chains of mouse IgM and IgA Source: Pepsin digest of Rabbit Anti-Mouse IgG(H+L) (SB Cat. No. 6175) Cross Adsorption: Pooled human sera and immunoglobulins; may react with immunoglobulins from other species …

Specificity: Reacts with the heavy chain of rat IgM Source: Pooled antisera from goats hyperimmunized with rat IgM Cross Adsorption: Rat IgG; may react with immunoglobulins from other species Purification: Affinity chromatography on pooled rat IgM covalently linked to agarose Isotype: …

Specificity: Reacts with the heavy and light chains of human IgG, IgM, and IgA Source: Pepsin digest of Goat Anti-Human Ig (SB Cat. No. 2010) Cross Adsorption: None; may react with immunoglobulins from other species Purification: Isotype: Goat F(ab')2 IgG Format/Conjugate: UNLB…

Specificity: Reacts with the heavy chain of human IgD Source: Pooled antisera from goats hyperimmunized with human IgD Cross Adsorption: Human IgG, IgM, and IgA; may react with IgD from other species Purification: Affinity chromatography on human IgD covalently linked to agarose …

CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and…

CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19…

CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and…

CD18 represents the common ß2 integrin subunit that associates non-covalently with the a/ß chains of CD11a, CD11b, and CD11c to form various integrin heterodimers. It is expressed strongly on lymphocytes and monocytes and weakly on granulocytes. CD18 mediates a variety of heterotypic and homotypic…

Specificity: Reacts with the heavy chain of mouse IgM Source: Pooled antisera from goats hyperimmunized with mouse IgM Cross Adsorption: Mouse IgG and IgA; may react with immunoglobulins from other species Purification: Affinity chromatography on mouse IgM covalently linked to agarose …

Specificity: Reacts with the heavy and light chains of human IgG and the light chains of human IgM and IgA Source: Pooled antisera from rabbits hyperimmunized with human IgG Cross Adsorption: None; may react with immunoglobulins from other species Purification: Affinity chromatography on…

CD45RB represents an exon B-dependent form of CD45 glycoprotein. It is expressed at high density on peripheral B cells, the suppressor/cytotoxic subpopulation of T lymphocytes, a subset of helper T cells, most thymocytes, and at low density on macrophages and dendritic cells.

Specificity: Reacts with the heavy chain of mouse IgG1 Source: Pooled antisera from goats hyperimmunized with mouse IgG1 Cross Adsorption: Mouse IgG2a, IgG2b, IgG3, IgM, and IgA; may react with immunoglobulins from other species Purification: Affinity chromatography on mouse IgG1…

The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid…

The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid…

Specificity: Reacts with the heavy and light chains of chicken IgY Source: Pooled antisera from goats hyperimmunized with IgY Cross Adsorption: None; may react with immunoglobulins from other species and the light chains of other chicken immunoglobulins Purification: Affinity…

Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2,…

The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid…

Specificity: Reacts with the heavy and light chains of mouse IgG and the light chains of mouse IgM and IgA Source: Pepsin digest of Rabbit Anti-Mouse IgG(H+L) (SB Cat. No. 6175) Cross Adsorption: Pooled human sera and immunoglobulins; may react with immunoglobulins from other species …

Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral…

Specificity: Reacts with the heavy and light chains of turkey IgY Source: Pooled antisera from goats hyperimmunized with IgY Cross Adsorption: None; may react with immunoglobulins from other species and the light chains of other turkey immunoglobulins Purification: Affinity…

Specificity: Reacts with human ? light chains Source: Pepsin digest of Goat Anti-Human Kappa, Mouse ads (SB Cat. No. 2061) Cross Adsorption: Human ? light chains; mouse immunoglobulins and pooled sera; may react with ? light chains from other species Purification: Isotype: Goat…

Specificity: Reacts with the heavy chain of mouse IgG2a Source: Pooled antisera from goats hyperimmunized with mouse IgG2a Cross Adsorption: Mouse IgG1, IgG2b, IgG3, IgM, and IgA; human immunoglobulins and pooled sera; may react with immunoglobulins from other species Purification: …