Spectinomycin is an aminocyclitol antibiotic, closely related to the aminoglycosides, it inhibits protein synthesis (elongation) by interfering with peptidyl tRNA translocation. Mutation in rpsE (the gene for ribosomal protein S5) prevents binding of spectinomycin. Specinomycin is used in cell…

TESTED AGAINST BOTH SENSITIVE and RESISTANT CELLS. Spectinomycin Dihydrochloride Pentahydrate MOLECULAR BIOLOGY GRADE Spectinomycin is an aminocyclitol antibiotic which acts by binding to the 30S subunit of the bacterial ribosome and inhibiting protein synthesis. Its activity is generally…