Polymyxin B Sulfate is a mixture of Polymyxin B1 and Polymyxin B2 Sulfate, obtained from Bacillus polymyxia strains. Inhibits gram-negative organisms in vitro Binds to and interferes with permeability of bacterial cytoplasmic membrane Inhibits Ca2+ dependent protein kinase C (PKC) …

Polymyxin B Sulfate is a mixture of Polymyxin B1 and Polymyxin B2 Sulfate, obtained from Bacillus polymyxia strains. Polymyxin B inhibits gram-negative organisms in vitro and is also reported to inhibit Ca2+ dependent protein kinase C (PKC). It binds to and interferes with the permeability of the…