CGRP is a 37 amino acid peptide synthesized in the central and peripheral nervous system from a calcitonin/CGRP gene complex. Two isoforms have been described which differ by three amino acids and display similar biological activities: CGRP-α, which is produced by alternative splicing of a…

Lyophilized fluorescent substrate.

Atriopeptin is a 28 amino acid peptide synthesized primarily in cardiac atria. This peptide hormone acts in opposition to angiotensin II in regulating renal, hemodynamic, and endocrine function. Atriopeptin is released in response to the increased pressure and mechanical stretch of the right atrium…

GH is a polypeptide hormone with a molecular weight of 23 kDa released from somatotropes of the anterior pituitary. It is regulated by several neurotransmitters and neuropeptides. Among other functions it plays an essential role in regulating body growth. Plasma GH levels in humans are markedly…

This EIA utilizes plates coated with a polyclonal antibody specific for murine/rat leptin. A biotin-labeled polyclonal antibody and streptavidin-horseradish peroxidase are used for detection.

Cayman’s Histamine EIA is a derivitization-amplified competitive enzyme immunoassay which detects histamine within the range from 40 to 5,500 pg/ml. The assay can be used for the analysis of histamine in blood (plasma or serum) without extraction or purification. The use of other sample types…

GFAP is a 40-53 kDa monomeric molecule found only in adult glial cells of the central nervous system (CNS) and represents the major part of the cytoskeleton of astrocytes. Traumatic injury to the adult CNS results in a rapid inflammatory response by the resident astrocytes, characterized mainly by…

Lyophilized fluorescent substrate.

Angiotensin II is a primary reactive vasoconstrictor, the main stimulus for aldosterone release, and one of the causative factors of chronic hypertension. The active angiotensin II octapeptide is released via a tightly controlled series of prohormones and proteases. Normal human plasma angiotensin…

This EIA kit specifically measures the acylated form of ghrelin.

Cayman’s 8-Isoprostane Affinity Column provides a specific and convenient means for the purification of 8-isoprostane (8-iso PGF2α) from urine and plasma samples. Each column contains 0.5 ml of affinity sorbent (mouse anti-8-isoprostane monoclonal antibody covalently bound to Sepharose 4).

Lyophilized fluorescent substrate.

Lyophilized fluorescent substrate.

CGRP is a 37 amino acid peptide synthesized in the central and peripheral nervous system from a calcitonin/CGRP gene complex. Two isoforms have been described which differ by three amino acids and display similar biological activities: CGRP-α, which is produced by alternative splicing of a…

Purified MIS for ELISAs.

The assay utilizes plates coated with a monoclonal capture antibody specific for the human leptin receptor and a HRP-conjugated monoclonal antibody for detection.

AcSDKP is a tetrapeptide growth regulatory hormone which inhibits the proliferation of hematopoietic stem cells. The dipeptidase angiotensin converting enzyme (ACE) actively metabolizes circulating AcSDKP, giving it a brief plasma half-life of 4 to 5 minutes. ACE inhibition is a major therapeutic…

Insulin is a polypeptide hormone with a molecular weight of 6 kDa, composed of two peptides chains, A and B, cross-linked by two disulfide bonds and synthesized by the b cells of the islets of Langherans of the pancreas. Insulin influences many metabolic functions of the body. Its best known action…

FABP4 is a 15 kDa member of the intracellular FABP family, which is known for the ability to bind fatty acids and related compounds (bile acids or retinoids). FABP4 is expressed in a differentiation-dependent fashion in adipocytes and is a critical gene in the regulation of the biological function…

Application: ELISA and WB

A leptin standard set.

Leptin is a 16 kDa protein hormone encoded by the obese (ob) gene with important effects in metabolism and regulation of body weight. Leptin has dual actions, decreasing appetite and increasing energy consumption. The primary effect of leptin appears to be mediated by leptin receptors expressed…

This EIA is based on a double-antibody sandwich technique which utilizes a murine adiponectin-specific monoclonal capture antibody and a HRP-conjugated polyclonal antibody for detection.

An assay for detection of TrxR activity.

This EIA kit specifically measures the acylated form of ghrelin.

Prolactin is a 199 amino acid (23 kDa) neuropeptide best known for its role in the initiation and maintenance of lactation. The hormone is secreted by the lactotrophic cells of the anterior pituitary. Prolactin concentrations in the circulation rise continually from the fifth week of pregnancy…