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Fructose 1,6-bisphosphatase-1 Inhibitor
Cayman ChemicalA cell-permeable benzoxazolo-sulfonamide compound that blocks human FBPase-1 enzymatic activity by competing at the AMP allosteric binding site (IC50 = 3.4 µM; Ki = 1.1 µM); blocks glucose production in starved rat hepatoma cells (IC50 = 6.6 µM).
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