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AG-1024
LKT LabsAG-1024 is a tyrphostin that inhibits IGF-1R, exhibiting anticancer chemotherapeutic activity. In hepatocellular carcinoma cells and breast cancer cells, AG-1024 increases levels of cytochrome C, decreases activation of ERK, and inhibits invasion and p
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AG-1024
Cayman ChemicalA selective inhibitor of IGF-1R that inhibits insulin-stimulated cellular proliferation and IGF-1R autophosphorylation with IC50 values of 0.4 and 7 μM, respectively; inhibits proliferation of human breast cancer MCF-7 cells (10 nM) and human prostate cancer DU145 cells…
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