Antineoplastic agent that acts as an antimetabolite of folic acid. Inhibits the enzyme dihydrofolate reductase and prevents formation of tetrahydrofolate. Protect from light.

Formula: C20H24N8O6 Formula weight: 472.45 CAS Number: 59-05-2 UN Number: UN1544 Hazard Class: 6.1 Packing Group: III Harmonized Tariff Code:  2933.59 Hazard Statements: H301-H360-H315-H319 Toxic if swallowed. May damage fertility or the unborn child. Causes skin irritation.…

An analog of folic acid and aminopterin that is used in the treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions; induces adenosine release, inhibits the metabolism of folic acid, and blocks key enzymes in the synthesis of purines and pyrimidines…

Grade: USP CAS No.: 59-05-2 UN No.: UN2811 Class: 6.1 Pkg. Group: PG III

CAS: 59-05-2 EC No: 200-413-8 MDL No: MFCD00150847 RTECS: MA1225000 UN No: UN1544; Haz Class: 6.1; Packing Group: III Powder Molecular Formula: C₂₀H₂₂N₈O₅ MW: 454.44 Melting Point: 185-204°

Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of…