A broad-spectrum inhibitor of TACE, other ADAMs, and other MMPs; inhibits PMA-induced shedding of various cell surface proteins, such as TGF-α, βAPP, L-selectin, IL-6 receptor α subunit (IC₅₀ = 10 µM); prevents mobilization of the growth factors TGF-α and…

Synonym(s): TNF-^b Protease Inhibitor-2 Formula: C19H37N5O5 Formula weight: 415.53 CAS Number: 187034-31-7 Harmonized Tariff Code:  3504.00