Synonyms: 33-epi-chloro-33-desoxyascomycin; Picrolimus Molecular Formula: C43H68ClNO11 Molecular Weight: 810.45 Linear Structural Formula: C43H68ClNO11 MDL Number: MFCD00901792 Purity: >=97% (HPLC) Storage: 2-8C Biochem Physiol Actions: Pimecrolimus, also known as…

A macrolactam that binds to macrophilin-12 and inhibits calcineurin as well as prolyl isomerase; the activation of T cells by allogeneic dendritic cells (IC₅₀ = 0.55 nM) and suppresses the generation of pro-inflammatory cytokines; used in countering inflammatory skin diseases, such as…