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Tubastatin A (trifluoroacetate salt)
Cayman ChemicalPotent HDAC6 inhibitor (IC50 = 15 nM) with 1,000-fold selectivity against all other HDAC isoforms (IC50s >16 μM), excluding HDAC8 (IC50 = 0.9 μM); induces α-tubulin hyperacetylation at 2.5 μM in primary cortical neuron cultures; displays dose-dependent neuronal protection of…
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