Synonyms: Fibroblast growth factor 4; HBGF4; Heparin-binding growth factor 4; K-fibroblast growth factor; KFGF
Purity: >=95% (SDS-PAGE)
Storage: -70C
UNSPSC Code: 12352200
General description: The FGF4 (fibroblast growth factor 4) gene is mapped to human chromosome 11q13.3. It is expressed during early embryonic development. In adults, it is strongly expressed in the testis.
Biochem/physiol Actions: FGF4 (fibroblast growth factor 4) helps in preserving the self-renewal capability of normal stem cells. The encoded protein has the ability to interact with FGFR1c (FGF receptor 1c) and FGFR2c. It also binds to FGFR3c and FGFR4, but to a lesser extent. FGFR4 is also required for cellular differentiation, morphogenesis and proliferation. It modulates proliferation and differentiation of normal stem cells, progenitor cells and cancer cells.
Physical form: Lyophilized from a PBS solution.
Reconstitution: Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Preparation Note: Centrifuge the vial prior to opening.
RIDADR: NONH for all modes of transport
WGK Germany: 3