NUCLEOSHELL® core-shell silica phases for HPLC
NUCLEOSHELL® Core-shell technology provides
- Better resolution at lower back pressure and shorter retention time
- Solid core of silicon dioxide
- Homogeneous shell of porous silica
- Highest efficiency compared to traditional totally porous materials
- Particle size 2.7 µm (core 1.7 µm); specific surface 130 m2/g
- RP 18 and RP 18plus phases are also available with particle size 5 µm (core 3.8 µm); specific surface 90 m2/g
- Lower back pressure also allows use on conventional LC systems
- Pressure stability up to 600 bar
NUCLEOSHELL® HILIC
Core-shell technology silica phase for Hydrophilic Interaction Chromatography
Key features:
- Based on core-shell particle technology for fast and efficient HPLC
- Ideal for reproducible and stable chromatography of highly polar analytes
- Very short column conditioning period
Technical characteristics:
- Ammonium – sulfonic acid modified silica
- Pore size 90 Å
- Particle size 2.7 μm
- pH stability 2–8.5
- Carbon content 1.3 %
Recommended application: hydrophilic compounds such as organic polar acids and bases, polar natural compounds, nucleosides, oligonucleotides, amino acids, peptides, water soluble vitamins