For surfactant analysis using high-sensitivity detection, the column of choice is the Acclaim™ Surfactant Plus LC Columns. This new generation of high-efficiency silica-based columns features exceptionally low bleed for use with charged aerosol detectors (CAD) and mass spectrometers (MS). The columns provide selectivity similar to the Acclaim Surfactant columns for sensitive separation of a wide variety of surfactants. The advanced surface chemistry provides both reversed-phase and anion-exchange retention mechanisms and significantly improves the resolution of surfactants.