Synonyms: Sodium borocyanohydride; Sodium cyanoborohydride; Sodium cyanotrihydroborate
CAS Number: 25895-60-7
Formula: CH3BNNa
Formula Weight: 62.84
Linear Formula: NaBH3CN
MDL No.: MFCD00003516
Density: 0.915 g/mL at 25 C
UNSPSC Code: 12352000
General description: Sodium cyanoborohydride is a versatile reducing agent stable in aqueous solution at pH 7.2. It is a weaker reducing agent as compared to NaBH4. It effectively reduces Schiff bases. NaCNBH4 participates in the reductive methylation for the efficient and selective conversion of the e-amino groups of lysyl residues in proteins to the mono- and dimethyl derivatives.
Application: Sodium cyanoborohydride may be used in the following studies:. As reducing agent for the in vitro radiolabeling of proteins by reductive alkylation.. Reduction of aldehydes and ketones.. Selective deoxygenation of aldehydes and ketones.. Preparation of colloidal gold particles of varying sizes.
Application: Reactant for:. Direct conversion of heterocyclic aldehydes to esters (oxidizing behavior). Reductive amination reactions. Intramolecular reductive cyclization reactions. Reductions reactions. Preparation of dicyanoborate-based ionic liquids as hypergolic fluids for bipropellants
RIDADR: UN 1992 6.1(3) / PGII
WGK Germany: 3
Flash Point(F): 1.4 F
Flash Point(C): -17 C
R Codes: 11-19-23/24/25-32-36/37/38-40-50/53
S Codes: 16-26-36/37-45-61
IOD Codes: F,T,N
Symbol: GHS02, GHS05, GHS06, GHS08, GHS09
Signal Word: Danger
Hazard Statements: H225-H301 + H311 + H331-H314-H335-H351-H410
Precautionary statements: P210-P280-P304 + P340 + P310-P305 + P351 + P338-P370 + P378-P403 + P235