Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. PEGs are susceptible to oxidative degradation in the presence of air. Minimizing the exposure of PEG to elevated temperatures and/or exposure to oxygen, or addition of an antioxidant can limit the amount of degradation. PEGs do not hydrolyze or deteriorate upon storage. PEGs do not support the growth of molds. PEG is incompatible with phenol and may reduce the antimicrobial action of other preservatives.
PEG has been used in the precipitation of proteins, as a fusing agent in enhancing the effect of macrophages on hybridoma, in the separation and purification of biomolecules, and in induction of cell hybridization. PEG 8000, can be used to precipitate DNA. PEG has also been used to recover pathogenic viruses and human rotaviruses from water, oyster and sediment samples. PEG has demonstrated to have anticell proliferation and antitumor effects via induction of apoptosis.
Key Applications: Precipitation of DNA
Application Areas: Molecular Biology, Immunology
Product Type: Biochemicals
Biochemical Category: Surfactants
Chemical Class: Surfactants
Density: 1.1-1.2 g/mL (Lit.)
Auto Ignition: 581°F (Lit.)
Melting Point: 56 - 66°C
Vapor Density: >1 (vs air) (Lit.)
Vapor Pressure: <0.01 mmHg at 20°C (Lit.)
Presentation: Off-White Powder
Format: Powder
pH: 5.0 - 7.0 (5% aq soln)
Solubility: Soluble in aqueous solution (50 mg/mL-clear, colorless solution).
Storage & Handling: Store at Room Temperature (15-30°C).