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Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin, whereas hydroxocobalamin (vitamin B12a, OHCbl) and cyanocobalamin (CNCbl) are storage and delivery forms.

Vitamin B12 plays a role in the synthesis of myelin. It is a cofactor for two enzymes, methionine synthase and L-methylmalonyl-CoA mutase. The compound is also used as an antipernicious anemia factor.

Biosynthesis of the basic structure of the vitamin is accomplished only by bacteria(which usually produce hydroxocobalamin). Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine.

Purity: ≥96%

Key Applications: Antipernicious anemia factor, Cofactor, Treatment of vitamin B12 deficiency, cyanide poisoning, and hereditary deficiency of transcobalamin II

Product Type: Biochemicals

Melting Point: >300°C(Lit.)

Presentation: Red Powder

Format: Powder

Loss on Drying: ≤12%

Solubility: Soluble in alcohol; slightly soluble in H2O.

Storage & Handling: Store at +4°C, desiccate.

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Product Detail
Thomas No.
C829M72
Mfr. No.
02103271.2
CAS #
68-19-9
Description
Vitamin B12, 250mg
Grade
~99% Purity
Packaging Size
250 mg
Packaging Type
Bottle, Glass, Amber
list price/quantitytotal
$0.00
Thomas No.
C829M73
Mfr. No.
02103271.5
CAS #
68-19-9
Description
Vitamin B12, 500mg
Grade
~99% Purity
Packaging Size
500 mg
Packaging Type
Bottle, Glass, Amber
list price/quantitytotal
$0.00
Thomas No.
C829M74
Mfr. No.
0210327101
CAS #
68-19-9
Description
Vitamin B12, 1g
Grade
~99% Purity
Packaging Size
1 g
Packaging Type
Bottle, Glass, Amber
list price/quantitytotal
$0.00
Thomas No.
C829M75
Mfr. No.
0210327105
CAS #
68-19-9
Description
Vitamin B12, 5g
Grade
~99% Purity
Packaging Size
5 g
Packaging Type
Bottle, Glass, Amber
list price/quantitytotal
$0.00
$0.00 (0 Items)
Product is restricted and can only be purchased by customers with a web profile linked to a Thomas Business Account - Click here to login or create your web profile. If you do not have a Thomas Business Account, please Contact Us and someone will respond with details on how to apply for a business account with us.

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