Synonyms: 2-(7-Methyl-1H-indol-3-yl)quinoline
Molecular Formula: C18H14N2
Molecular Weight: 258.32
Linear Structural Formula: C18H14N2
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: VPC-13566 is Binding Function 3 (BF3)-specific inhibitor of the androgen receptor. VPC-13566 potently inhibits AR transcriptional activity by displacement of the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines including an enzalutamide-resistant cell line and inhibits the growth of AR-dependent prostate cancer xenograft in mice.