End product of the urea cycle. A topical keratolytic agent.
Synonyms: Urea; Carbamide, Carbonyl Diamide; Carbamide; Carbonyldiamide
Molecular Formula: CH4N2O
Molecular Weight: 60.06
Linear Structural Formula: NH2CONH2
MDL Number: MFCD00008022
Purity: >=98%
Melting Point: 132-135 C (lit.)
Density: 1.335 g/mL at 25 C (lit.)
Application: Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.
Legal Information: CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany