TS-2 is a strong organic base formulated to solubilize biological materials. Its high water holding capacity will incorporate up to 450 mg of aqueous volume using just 1 ml of TS-2. This factor alone makes TS-2 an economical product to use. TS-2 is compatible with all aromatic hydrocarbon based scintillation cocktails and eliminates problems related to chemiluminescence. This provides accurate sample reproducibility.
The ratio of sample weight or volume to the TS-2 volume will vary. Some typical examples are listed below:
Sample Volume TS-2 Volume Plasma - 0.4ml to 1.0ml
Dilute Nucleic Acids - 0.5ml to 1.0ml
Dilute Amino Acids - 0.5ml to 1.0ml
Protein Homogenates - 0.4ml to 1.0 ml
Most sample digestion can be performed at room temperature, which also reduces the effects of color quenching. If quicker digestion is preferred this can be achieved by heating the sample up to 50°C for various time periods.