Synonyms: 5-[3-(Ethylsulfonyl)phenyl]-3,8-dimethyl-N-(1-methyl-4-piperidinyl)-9H-pyrido[2,3-b]indole-7-carboxamide; TAK 901
Molecular Formula: C28H32N4O3S
Molecular Weight: 504.64
Linear Structural Formula: C28H32N4O3S
MDL Number: MFCD18782651
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: TAK-901 is a potent and tight-binding Aurora B kinase inhibitor. TAK-901 targets multiple kinases in vitro, but appears to mainly target Aurora B in cells and in vivo. TAK-901 suppresses cellular histone H3 phosphorylation and induced polyploidy.