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Synonyms: Streptomycin sulfate salt
Molecular Formula: C21H39N7O12 · 1.5H2O4S
Molecular Weight: 728.69
Linear Structural Formula: C21H39N7O12 · 1.5 H2SO4
MDL Number: MFCD00037023
Biochem Physiol Actions: Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation.Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin.Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria.
Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.