Synonym: Taurocholic acid sodium salt
CAS Number: 345909-26-4
Empirical Formula (Hill Notation): C26H44NNaO7S · xH2O
Molecular Weight: 537.68 (anhydrous basis)
Beilstein Registry Number: 3901620
EC Number: 205-653-7
MDL Number: MFCD00150819
PubChem Substance ID: 24888592
Other Notes
For the solubilization of unconjugated bilirubin
Preparation Note
Sodium taurocholate hydrate yields a clear, colorless solution in water at 50 mg/ml.
Application
Sodium taurocholate hydrate was used as an emulsifier in in situ preparation of digestive enzymes.
Biochem/physiol Actions
Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid. These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid.
Description: anionic
Assay: ≥97.0% (TLC)
Optical Activity: [α]20/D +23±1°, c = 3% in H2O (dry matter)
Impurities: ≤1% taurine; ≤2% cholic acid
Solubility: H2O: soluble50 mg/mL, clear