Synonyms: 3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide dihydrochloride; Smoothened Agonist
Molecular Formula: C28H28ClN3OS · 2HCl
Molecular Weight: 562.98
Linear Structural Formula: C28H28ClN3OS · 2HCl
Purity: >=98% (HPLC)
Storage: -20C
Biochem Physiol Actions: SAG is a potent and cell-permeable smoothened (Smo) agonist that activates Hedgehog pathway and counteracts Cyclopamine inhibition of Smo.