Retigabine is an antiepileptic drug, which activates neuronal KCNQ-type K+ channels by inducing a large hyperpolarizing shift of steady-state activation.
Synonyms: D-23129; Ezogabine; N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester
Molecular Formula: C16H18FN3O2
Molecular Weight: 303.33
Linear Structural Formula: C16H18FN3O2
MDL Number: MFCD04307735
Purity: >=98.0% (HPLC)
Storage: 2-8C
Application: Retigabine may be used as a reference standard in the determination of retigabine in biological matrices using high-performance liquid chromatography coupled with tandem mass spectrometry with positive ion atmospheric pressure chemical ionization (HPLC-APCI-MS/MS).
Biochem Physiol Actions: Retigabine (Ezogabine) is a Kv7.2-7.5 (KCNQ2-5) neuronal potassium channel opener witrh anticonvulsant activity.