Synonyms: MAPK13; PRKM13; SAPKA4
Purity: >=70% (SDS-PAGE)
Activity: activity: 220-298 nmol/min·mg
Storage: -70C
UNSPSC Code: 12352200
Biochem/physiol Actions: p38d (SAPK4) is a member of the p38 MAPK family and is activated by chemical and environmental stresses as well as by proinflammatory cytokines. p38d has a TGY dual phosphorylation motif and is activated in response to cellular stresses and proinflammatory cytokines.MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
Physical form: Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
RIDADR: NONH for all modes of transport
WGK Germany: 1