Synonyms: Polymyxin B sulfate salt
Formula: C55H96N16O13 · 2H2SO4
Formula Weight: 1385.61
CAS No.: 1405-20-5
Storage Temperature: 2-8°C
Application: Used as immobilized (substrate bound) agent for removal of endotoxins.
Biochem/physiol Actions: Antibiotic with bactericidal action on E. coli.1,2 Binds to the lipid A portion of bacterial lipopolysaccharides.3 Induces pore formation in the membranes of cortex cells from excised sorghum roots.4
Mode of Action: Binds to and interferes with the permeability of the cytoplasmic membrane.
Antimicrobial spectrum: Gram-negative bacteria.
Other Notes: Mixture of Polymyxin B1 and B2 sulfate.
Form: powder
Solubility: H2O: soluble50 mg/mL (Stock solutions should be filter sterilized and stored at 2-8-á°C. Stable at 37-á°C for 5 days.)
Storage Temp.: 2-8°C
Suitability: meets USP testing specifications