Acetyl carnitine is one of the major acylcarnitines produced during the transport of long-chain fatty acids in the body.
Synonyms: ®-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride; ALC; ALCAR; R-(-)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride
Molecular Formula: C9H17NO4 · HCl
Molecular Weight: 239.7
Linear Structural Formula: C9H17NO4 · HCl
MDL Number: MFCD00082230
Purity: >=96.0% (HPLC); 96.0-104.0% (AT)
Storage: 2-8C
Application: O-Acetyl-L-carnitine hydrochloride may be used as a precursor for the preparation of O-Acetyl-L-carnitine, which in turn may be used as an analytical reference standard for the determination of the analyte in biological samples by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) technique.
Biochem Physiol Actions: Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.