Synonyms: MCF; Chloroformic acid methyl ester
CAS Number: 79-22-1
Formula: C2H3ClO2
Formula Weight: 94.5
Linear Formula: ClCOOCH3
MDL No.: MFCD00000639
Purity: 0.99
Boiling Point: 70-72 C(lit.)
Density: 1.223 g/mL at 25 C(lit.)
Refractive Index: n20/D 1.387(lit.)
Storage: 2-8C
Beilstein Registry Number: 605437
EC Number: 201-187-3
UNSPSC Code: 12352100
Application: Methyl chloroformate (MCF) is generally used for the derivatization of functional groups such as carboxylic acids, amines, and phenols.MCF can also be used:. To activate 3-acylpyridines for nucleophilic addition with alkynyltin reagents to form 2,3-disubstituted 1,2-dihydropyridines.. Chloroesterification of terminal alkynes to form β-chloro-α,β-unsaturated esters.. As an electrophilic reagent to mediate the reaction of pyridine with lithium dialkyl- or diarylcuprates to form 4-substituted 1,4-dihydropyridine derivatives.. To convert nitronates into methoxycarbonyl nitronates.
RIDADR: UN1238 - class 6.1 - PG 1 - Methyl chloroformate
WGK Germany: 2
Flash Point(F): 50 F
Flash Point(C): 10 C
R Codes: 11-21/22-26-34
S Codes: 14-26-28-36/37/39-45-46-63
IOD Codes: F,T+
Symbol: GHS02, GHS05, GHS06
Signal Word: Danger
Hazard Statements: H225-H302 + H312-H314-H330
Precautionary statements: P210-P260-P280-P284-P305 + P351 + P338-P310