• PRODUCT AVAILABILITY: Did you know you can view a product's availability right on the product page? Simply enter the quantity you want to purchase and the current availability will appear below the item.

  • Product is restricted and can only be purchased by customers with a web profile linked to a Thomas Business Account - Click here to login or create your web profile. If you do not have a Thomas Business Account, please Contact Us and someone will respond with details on how to apply for a business account with us.

MilliporeSigma

Liproxstatin-1 >98% (HPLC)

Not yet rated

Synonyms: N-[(3-Chlorophenyl)methyl]-spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine; N-[(3-chlorophenyl)methyl]spiro[4H-quinoxaline-3,4'-piperidine]-2-amine

Molecular Formula: C19H21ClN4

Molecular Weight: 340.85

Linear Structural Formula: C19H21ClN4

MDL Number: MFCD14948691

Purity: >98% (HPLC)

Storage: -20C

Application: Liproxstatin-1 has been used as a cell death inhibitor in the cell viability assay and for the determination of lipid peroxidation.

Biochem Physiol Actions: Liproxstatin-1 is a potent inhibitor of ferroptosis, a non-apoptotic form of cell death characterized by iron-dependent accumulation of lethal lipid reactive oxygen species (ROS). Liproxstatin-1 suppressed ferroptosis in human cells and in an ischaemia/reperfusion-induced tissue injury model in mice. Knockout of glutathione peroxidase 4 (Gpx4) Has been shown to cause cell death by ferroptosis. Liproxstatin-1 was able to suppress ferroptosis in Gpx4 knock-out mice.

Please Enter Your Order Info

Filter by:

  • Clear Filters
Product Detail
Thomas No.
CHM01U044
Mfr. No.
SML1414-25MG
Description
SML1414-25MG Liproxstatin-1 >98% (HPLC)

list price/quantitytotal
$0.00
Thomas No.
CHM01U035
Mfr. No.
SML1414-5MG
Description
SML1414-5MG Liproxstatin-1 >98% (HPLC)

list price/quantitytotal
$0.00
$0.00 (0 Items)
Product is restricted and can only be purchased by customers with a web profile linked to a Thomas Business Account - Click here to login or create your web profile. If you do not have a Thomas Business Account, please Contact Us and someone will respond with details on how to apply for a business account with us.

Write A Review