Synonyms: N-[2-Methoxy-4-(4-morpholinyl)phenyl]-6-(1H-pyrazol-3-yl)-2-pyridinecarboxamide
Molecular Formula: C20H21N5O3
Molecular Weight: 379.41
Linear Structural Formula: C20H21N5O3
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: JH-I-25 is a potent and selective type I inhibitor of IRAK1 and IRAK4 (interleukin-1 receptor-associated kinase 1 and 4). JH-I-25 binds preferentially to the unphosphorylated the ATP-site of the kinase in its active, DFG-in, state.