Synonyms: 4-(2-Methylpropyl)-benzeneacetic acid; 4-Isobutylphenylacetic acid
Molecular Formula: C12H16O2
Molecular Weight: 192.25
Linear Structural Formula: C12H16O2
MDL Number: MFCD00864374
Purity: >=95% (HPLC)
Storage: -20C
Biochem Physiol Actions: Ibufenac is a non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen that was withdrawn for hepatotoxicity. It inhibits cyclooxygenases COX-1 and -2 activity with IC50 values of 17.4 and 13.1 muM, respectively and > 40 muM for 5-LOX. It has been used in studies of drug-induced hepatotoxicity.