Hyacinth BMT activator (also known as 5-Benzylmercapto-1H-tetrazole or BTT) demonstrates important advantages in the syntheses of oligonucleotides:
- Coupling efficiencies of 99% with impeccable quality
- Lower percentage of n - 1 sequences
- Dramatic reduction of coupling times to under 3 minutes in RNA syntheses
- Efficient RNA synthesis using 50% or less TBDMS, ACE or TOM monomer
- Excellent batch to batch consistency for reproducible and stable oligo production