Synonym: 4',5,7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CAS Number: 446-72-0
Empirical Formula (Hill Notation): C15H10O5
Molecular Weight: 270.24
Beilstein Registry Number: 263823
EC Number: 207-174-9
MDL Number: MFCD00016952
PubChem Substance ID: 24278036
Biochem/physiol Actions
nhibitor of tyrosine protein kinase; competitive inhibitor of ATP in other protein kinase reactions. Antiangiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis.
Packaging
100 mg in poly bottle; 5, 25 mg in glass bottle
Biological Source: synthetic
Assay: =98% (HPLC)
Form: powder
Color: off-white
Solubility: DMSO: soluble; ethanol: soluble
Storage Temp.: -20°C
Gene Information: human ... AKT1(207), CYP19A1(1588), EGFR(1956), ESR1(2099), ESR2(2100)
mouse ... Esr1(13982), Hexa(15211)
rat ... Adora1(29290), Adora2a(25369), Ar(24208)