Synonyms: GALT; UDP glucose:alpha-D-galactose-1-phosphate uridyltransferase
CAS Number: 2599380
MDL No.: MFCD00131120
Storage: -20C
Enzyme Commission (EC) Number: 2.7.7.12 ( BRENDA | IUBMB )
UNSPSC Code: 12352204
Biochem/physiol Actions: Galactose-1-phosphate uridyltransferase (GALT) facilitates the simultaneous conversion of uridine diphosphoglucose (UDP-glucose) and galactose-1-phosphate (gal-1P) to uridine diphosphogalactose (UDP-galactose) and glucose-1-phosphate. Classic Galactosemia (CG) is an inherited metabolic condition caused by deficiency of GALT activity.
Physical form: Contains buffer salts as citrate and reduced glutathione
Unit Definition: One unit will form 1.0 mumole of glucose 1-phosphate from UDP-glucose, galactose 1-phosphate and NADP+ per min at pH 8.7 at 25 C as detected by a coupled system using phosphoglucomutase.
RIDADR: NONH for all modes of transport
WGK Germany: 3