Synonyms: EDC; N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide hydrochloride; EDAC; EDC; EDC hydrochloride; WSC hydrochloride
Molecular Formula: C8H17N3 · HCl
Molecular Weight: 191.7
Linear Structural Formula: C8H17N3 · HCl
MDL Number: MFCD00012503
Melting Point: 110-115 C (lit.)
Storage: -20C
Application: N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride has been used:
•for the immobilisation of trypsin onto self-assembled monolayers (SAMs)
•as a component for the preparation of collagen matrices
•for the preparation of phosphoethanolamine(PEt)-conjugated sepharose
Biochem Physiol Actions: Water soluble condensing reagent. EDAC is generally utilized as a carboxyl activating agent for amide bonding with primary amines. In addition, it will react with phosphate groups. EDAC has been used in peptide synthesis; crosslinking proteins to nucleic acids; and preparation of immunoconjugates as examples. Typically, EDAC is utilized in the pH range 4.0-6.0 without buffers. In particular, amine and carboxylate buffers should be avoided.
Form: crystalline
MP: 110-115°C(lit.)
Quality Level: PREMIUM
Solubility: H2O: ≤100 mg/mL
Storage Temp.: −20°C