(1R, 2R)-1,2-Bis(2-hydroxyphenyl)ethylenediamine or (R, R)-1,2-bis(2-hydroxyphenyl)-1,2-diaminoethane (HPEN) is commonly used in the stereoselective synthesis of enantiopure compounds.
Synonyms: (1R,2R)-1,2-Bis(2-hydroxyphenyl)-1,2-ethanediamine; (R,R) Diaminopharm Diamine; (R,R) Jik Chin Mother Diamine; (R,R) Mother Diamine
Molecular Formula: C14H16N2O2
Molecular Weight: 244.29
Linear Structural Formula: C14H16N2O2
MDL Number: MFCD09751760
Purity: 95% (HPLC)
Melting Point: 157-163 C
Application: (1R, 2R)-1,2-Bis(2-hydroxyphenyl)ethylenediamine can be used as a precursor for the synthesis of:
•Enantiomerically pure trans-3-arylpiperazine-2-carboxylic acid derivatives via diaza-Cope rearrangement (DCR).
•4,4'-(1,2-Diazaniumylethane-1,2-diyl)dibenzoate trihydrate by treating with terephthalaldehydic acid.