Synonym(s): (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-16α-methylprednisolone; Prednisolone F
Formula: C22H29FO5
Formula Weight: 392.46
CAS No.: 50-02-2
Purity: ≥80% (HPLC)
Application: An anti-inflammatory glucocorticoid with a range of effects on cell survival, cell signaling and gene expression. Use to study apoptosis, cell signaling pathways and gene expression.
Physical form: powder 2-8 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw
Storage: 2-8°C
Beilstein Registry Number: 2066651
EC No.: 200-003-9
Melting Point: 262-264°C(lit.)
Biochem/physiol Actions: Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
Reconstitution: To prepare 20 μg/ml stock solution: add 1 ml absolute ethanol; gently swirl to dissolve; add 49 ml sterile medium while mixing.
Empirical Formula (Hill Notation): C11H14O