Synonym(s): (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-16α-methylprednisolone; Prednisolone F
Formula: C22H29FO5
Formula Weight: 392.46
CAS No.: 50-02-2
Purity: ≥97%
Application: An anti-inflammatory glucocorticoid with a range of effects on cell survival, cell signaling and gene expression. Use to study apoptosis, cell signaling pathways and gene expression.
Physical form: powder 2-8 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw
Storage: 2-8°C
Beilstein Registry Number: 2066651
EC No.: 200-003-9
Melting Point: 262-264°C(lit.)
Biochem/physiol Actions: Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
Reconstitution: To prepare 20 μg/ml stock solution, add 1ml absolute ethanol per mg product; gently swirl to dissolve. Add 49 ml sterile medium per ml of ethanol added, while mixing, to acheive final concentration of 20 μg/ml.
Empirical Formula (Hill Notation): C8H5F3O