Complement C6 deficient serum human, for complement assays

Storage: -70C

UNSPSC Code: 12352202

Application: Complement C6 is one of the end terminals of the complement system contained in the membrane attack complex (MAC). A deficiency of C6 may result in an increased susceptibility to Neisseria meningitidis. Research has identified that a mutation which leads to a 31 bp deletion in exon 10 in the C6 gene results in C6 deficiency. A coagulation defect has also been observed in mice that are C6 deficient.

Physical form: Supplied as a solution in PBS, pH 7.4

Analysis Note: C6 is depleted by immunoadsorption as judged by a highly sensitive hemolytic assay.