Synonym: 7-Chlorotetracycline hydrochloride
CAS Number 64-72-2
Empirical Formula (Hill Notation) C22H23ClN2O8 · HCl
Molecular Weight 515.34
Beilstein Registry Number 3858364
EC Number 200-591-7
MDL number MFCD00082440
PubChem Substance ID 24892735
Application
Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.
Biochem/physiol Actions
Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens.
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacterial than tetracycline.
Mode of Resistance: Loss of cell wall permeability.
Packaging
5, 25, 100 g in glass bottle
assay: ≥75% (HPLC)
mp: 210-215 °C (dec.)(lit.)
storage temp.: −20°C