Synonyms: 1-Chloro-2,5-pyrrolidinedione; NCS
CAS Number: 128-09-6
Formula: C4H4ClNO2
Formula Weight: 133.53
Linear Formula: C4H4ClNO2
MDL No.: MFCD00005511
Purity: 0.98
Melting Point: 148-150 C (lit.)
Beilstein Registry Number: 113915
EC Number: 204-878-8
UNSPSC Code: 12352101
Application: N-Chlorosuccinimide (NCS) is a chlorinating and oxidizing reagent. It is more efficient when compared to other chlorinating agents, such as 1,3-dichloro-5,5-dimethylhydantoin (NDDH) and trichloroisocyanuric acid (TCCA) due to its high selectivity.It can be used for:. Conversion of diindenylzinc agent, [Zn(ind)2(pic)2]5 into 1-chloroindene.. Selective cleavage of tryptophanyl peptide bonds.. Chemoselective oxidation of primary alcohols to aldehydes catalyzed by 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) in the presence of tetrabutylammonium chloride under bi-phasic conditions.. Conversion of primary amides and aldoximes to their corresponding nitriles in the presence of triphenylphosphine.. α-Chlorination of acyl-chlorides.. Conversion of benzylic sulfides into α-chloro sulfides.
RTECS: UY1013500
RIDADR: UN 3261 8 / PGII
WGK Germany: 3
R Codes: 22-34
S Codes: 26-36/37/39-45
IOD Codes: C
Symbol: GHS05, GHS07
Signal Word: Danger
Hazard Statements: H302-H314
Precautionary statements: P280-P305 + P351 + P338-P310