Synonyms: Anti-ADP-ribosylation factor 1 GTPase-activating protein; Anti-ADP-ribosylation factor GTPase-activating protein 1; Anti-ARF1 GAP; Anti-GAP protein; ARF1-directed GTPase-activating protein
Storage: -20C
UNSPSC Code: 12352203
General description: ARFGAP1 is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine.
Immunogen: ARFGAP1 (NP_060679, 382-416)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ARFGAP1.
Physical form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: nwg