Synonyms: (2E)-3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one; 3PO (inhibitor of glucose metabolism)
Molecular Formula: C13H10N2O
Molecular Weight: 210.23
Linear Structural Formula: C13H10N2O
MDL Number: MFCD00224002
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: 3PO is a potent and selective inhibitor of PFKFB3 (6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase) that reduces glycolytic flux and suppresses glucose uptake. 3PO is selectively cytostatic to transformed cells and suppresses the growth of established tumor in mice.