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MilliporeSigma

2-Deoxy-D-glucose 6-phosphate sodium salt >=98% (HPLC)

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2-Deoxy-d-glucose (2DG) is a glucose molecule which has the 2-hydroxyl group replaced by hydrogen, so that it cannot undergo further glycolysis. As such, it acts to competitively inhibit the production of glucose-6-phosphate from glucose at the phosphoglucoisomerase level (step 2 of glycolysis). In most cells, glucose hexokinase phosphorylates 2-deoxyglucose, trapping the product 2-deoxyglucose-6-phosphate (2DG6P) intracellularly. 2DG & 2DG6P serve as good markers for tissue glucose uptake and hexokinase activity. For example, many cancers have elevated glucose uptake and hexokinase levels. 2DG6P undergoes only the first enzymatic reaction in the pentose phosphate pathway to generate 2-DG-6-phosphogluconolactone, which cannot be further metabolized.

Synonyms: 2-Deoxy-D-glucose 6-phosphate sodium salt

Molecular Formula: C6H13O8P · xNa+

Linear Structural Formula: C6H13O8P · xNa+

MDL Number: MFCD00057477

Purity: >=98% (HPLC)

Storage: -20C

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Thomas No.
CHM02G307
Mfr. No.
SMB00932-50MG
CAS #
33068-19-8
Description
SMB00932-50MG, 2-Deoxy-D-glucose 6-phosphate sodium salt >=98% (HPLC)
list price/quantitytotal
$0.00
Thomas No.
CHM02G308
Mfr. No.
SMB00932-25MG
CAS #
33068-19-8
Description
SMB00932-25MG, 2-Deoxy-D-glucose 6-phosphate sodium salt >=98% (HPLC)
list price/quantitytotal
$0.00
Thomas No.
CHM02G309
Mfr. No.
SMB00932-250MG
CAS #
33068-19-8
Description
SMB00932-250MG, 2-Deoxy-D-glucose 6-phosphate sodium salt >=98% (HPLC)
list price/quantitytotal
$0.00
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